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The content of this article or section is Star Trek canon referenced in the game or its lore. However, it does not directly appear in Star Trek Online. Broader Star Trek lore can be looked up on Memory Alpha and Memory Beta.
The U.S.S. Byzantium is a Federation starship in service to Starfleet in 2409. In that year, she led the U.S.S. Pollux and U.S.S. Sri Lanka against the Crystalline Entity, which was attacking a Federation colony in the Teneebia Sector.
Early in the battle, a fleet of Tholian starships forced the Byzantium on the defensive and bought time for the Entity to destroy the Pollox and the Sri Lanka. The Entity then fired a powerful Matter Conversion Beam, vaporizing 73 of the Byzantium's crew (including Captain Gorrus and half the bridge crew). The vessel's science officer managed to fire a sensor-scrambling probe that bought the ship enough time to escape the carnage and warp to safety.